A working directory of the CRM, marketing automation, sales intelligence, ad tech, and global agency holding groups that run modern go-to-market — and the AI-native platforms now automating outbound, creative, and campaign work outright. This is a first pass, built to be appended, not a finished census.
Through 2025 and into 2026, a wave of AI-native "digital worker" platforms — Artisan, 11x, Clay, Regie.ai — moved from lead scoring and email drafting to running entire outbound sequences: prospecting, personalised outreach, meeting booking, and follow-up, with little to no human SDR in the loop. Incumbent CRM and marketing-automation vendors responded by embedding agentic AI directly into their platforms — Salesforce's Agentforce, HubSpot's Breeze, and Microsoft's Copilot for Sales all launched or expanded through this window — while the global agency holding groups (WPP, Omnicom, Publicis, IPG) restructured creative and media-buying teams around AI-generated assets and programmatic automation.
The result is a profession bifurcating fast: a shrinking layer of strategic, relationship-led sales and brand work at the top, and an expanding layer of AI-run execution underneath it — sales intelligence, campaign ops, ad buying, and increasingly the first outbound conversation itself. The AI-Native Disruptor tier below tracks the platforms doing that displacing.
| Name | Tier | Headquarters | Founded | Key stat |
|---|